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CONTACT 1 | John Timms |
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The Cancer Proteomics Laboratory led by Dr John Timms was established 5 years ago. The laboratory's main research focus is on cell signalling in cancer and the identification of cancer biomarkers through the application of quantitative proteomic methodologies and biochemical and molecular biology techniques. Facilities include a biochemistry laboratory, dedicated clean rooms for high-sensitivity, low-contamination sample handling, fluorescence 2D difference gel electrophoresis (2D-DIGE) capability, liquid-handling robotics and liquid chromatography (LC) for protein and peptide separations. Mass spectrometry (MS) instrumentation for expression profiling, protein/peptide identification and characterisation includes a Thermo LTQ Orbitrap XL hybrid mass spectrometer with on-line Dionex3000 nano-LC system and Bruker Ultraflex MALDI-TOF/TOF instrument.
Agilent 1100 series HPLC with fraction collector used for off-line protein and peptide separations.
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Biorad Molecular Imager FX incorporating phosphorimager
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Bruker Ultraflex MALDI-TOF for high-throughput MALDI-based mass spectrometry
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Typhoon 9400 multiwavelength Imager for small to large format fluorescence imaging.
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Dionex Ultimate 3000 nano LC system used for on-line (to MS) peptide separations by reversed-phase LC (C18) . Linked to an LTQ Orbitrap XL mass spectrometer.
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Tecan Aquarius 96 tip liquid-handling robot and tip loader
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Item ID #
.Last Updated: 20th January, 2014
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